Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers (Admin Supp - Clinical Trial Not Allowed ) | PA 18 592

Opportunity Information: Apply for PA 18 592

Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers (Admin Supp - Clinical Trial Not Allowed) is an NIH administrative supplement opportunity (Funding Opportunity Number PA-18-592) run by the Office of Research on Women's Health (ORWH) together with participating NIH Institutes and Centers. The basic idea is to help talented researchers restart an active biomedical or behavioral research career after a significant pause, especially when the interruption was due to family responsibilities or other qualifying life circumstances. Instead of funding a brand-new standalone grant, NIH provides extra funds as an administrative supplement to an already-funded NIH research grant so the returning investigator can rejoin the research workforce, rebuild momentum, and refresh their scientific skills and knowledge in a real research setting.

The program is designed to support a structured re-entry period in which the candidate is placed on an existing NIH-funded project and carries out research either full-time or part-time, depending on what is feasible and appropriate for their situation. The emphasis is practical and career-oriented: the supplement is meant to provide salary and research support that allow the individual to update methods, regain familiarity with current literature and technologies, produce publishable work, and become competitive again for independent research funding or other research positions. Because this is a supplement to an active award, the work is expected to fit squarely within the scientific scope and mission of the parent grant and within NIH program priorities across the participating Institutes and Centers.

A key boundary of this opportunity is that it is labeled "Clinical Trial Not Allowed," meaning applications under this supplement mechanism are not intended to propose or support clinical trial activities as defined by NIH. The supported work should therefore remain in the non-clinical-trial space (for example, many forms of basic, translational, mechanistic, or behavioral research that do not meet NIH's definition of a clinical trial), and applicants need to ensure that the proposed re-entry activities align with that restriction.

Eligibility is tied to the administrative supplement structure. The applicant organization is generally a U.S.-based institution that already holds an eligible NIH research award and can request additional funds to support the re-entry candidate on that project. The source data lists "Public and State controlled institutions of higher education" as eligible applicants, and the full funding opportunity notice provides the detailed rules and any additional eligible organization types. The opportunity explicitly states that non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply, and that non-domestic components of U.S. organizations are also not eligible to apply. At the same time, "foreign components" as defined in the NIH Grants Policy Statement are allowed, which typically means that, under certain circumstances and with appropriate justification and NIH approval, specific project elements may be conducted outside the U.S. even though the applicant institution itself must be eligible and domestic.

From an administrative standpoint, this is a discretionary grant mechanism under the broad NIH assistance listing, with multiple CFDA numbers associated with participating NIH components (reflecting the fact that many Institutes and Centers can support re-entry supplements within their mission areas). The opportunity was created on January 25, 2018, and the original closing date listed in the provided data is July 22, 2021. Details such as an award ceiling and expected number of awards are not provided in the source snippet, which is common for administrative supplement announcements because the amount and availability can depend heavily on the parent grant, the candidate's proposed level of effort, the IC's policies, and yearly budget considerations.

In practical terms, this program functions as a bridge back into research: it leverages an active NIH-funded environment, provides time and resources for skill renewal and productivity, and aims to reduce the long-term career penalty that can follow a substantial research hiatus. The core outcome NIH is trying to promote is a successful transition from re-entry support to sustained, independent participation in biomedical and behavioral research within NIH mission areas.

• The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers (Admin Supp - Clinical Trial Not Allowed )" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.173, 93.213, 93.242, 93.273, 93.279, 93.286, 93.307, 93.310, 93.313, 93.351, 93.361, 93.393, 93.394, 93.395, 93.396, 93.398, 93.399, 93.840, 93.846, 93.847, 93.853, 93.855, 93.856, 93.859, 93.865, 93.866, 93.867, 93.879, 93.989.
• This funding opportunity was created on 2018-01-25.
• Applicants must submit their applications by 2021-07-22. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: Public and State controlled institutions of higher education.

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