Opportunity Information: Apply for CDC RFA GH21 2141

The Centers for Disease Control and Prevention (CDC), under the U.S. Department of Health and Human Services and through PEPFAR, released a cooperative agreement funding opportunity (CDC RFA GH21-2141, CFDA 93.067) focused on expanding and improving voluntary medical male circumcision (VMMC) services in Botswana as part of national HIV prevention efforts. The program is built on strong evidence that VMMC reduces a mans risk of acquiring HIV, and it aligns with UNAIDS-recommended prevention strategies for countries in sub-Saharan Africa where HIV burden is high and male circumcision coverage has historically been low. The main intent is to support Botswana in accelerating progress toward epidemic control by scaling up safe, high-quality VMMC services.

The opportunity is designed around a clear national coverage target: achieving 80 percent male circumcision coverage among males in the priority age group of 15 to 29 years to maximize near-term HIV prevention impact. Since 2009, PEPFAR and the Government of Botswana have supported large-scale implementation, resulting in more than 230,000 circumcisions performed. Even with that progress, the estimated coverage is still around 40 percent, which signals a need to increase the pace, strengthen service delivery, and improve approaches for reaching the remaining eligible population. The grant therefore emphasizes both expansion and quality, rather than simply counting procedures.

Programmatically, the recipient is expected to deliver VMMC services for males aged 15 years and older, concentrating on priority districts while maintaining the flexibility to shift resources geographically over the life of the award as needs change. That flexibility is important in public health programs where demand, service uptake, and local epidemic patterns can shift, requiring implementers to redeploy teams, supplies, and outreach to the areas where they will have the most impact. In addition to clinical service delivery, the work explicitly includes evidence-based demand creation, meaning structured community and client-focused strategies to increase informed uptake of VMMC. The opportunity also highlights continuous quality improvement (CQI), signaling that CDC expects the recipient to use routine data, quality standards, and ongoing performance management to improve safety, client experience, and efficiency over time.

From a funding standpoint, CDC anticipated approximately $5,000,000 in total funding for Year 1, contingent on the availability of funds. The notice states that the Year 1 award ceiling is listed as $0 (none), which generally indicates that a maximum per-award cap was not specified in the posting even though an overall estimated amount for the first year was provided. The announcement anticipated making one award, indicating CDC intended to fund a single primary implementing partner to lead or coordinate the effort at scale.

Eligibility was described as unrestricted, meaning applications were open to a broad range of organizations (subject to any clarifications in the full eligibility section of the notice). The application deadline for electronic submissions was March 12, 2021, by 11:59 p.m. Eastern Time. Overall, the grant opportunity is centered on accelerating VMMC coverage in Botswana through a combination of expanded access, stronger demand-generation approaches, and systematic quality improvement, with the ultimate goal of increasing prevention impact and helping move the country closer to controlling its HIV epidemic.

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Providing Quality Voluntary Medical Male Circumcision (VMMC) Services to Support HIV Prevention Efforts in Botswana under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on Jan 11, 2021.
  • Applicants must submit their applications by Mar 12, 2021 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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