Opportunity Information: Apply for CDC RFA CE21 2104
Preventing Violence Affecting Young Lives (PREVAYL) is a CDC-funded cooperative agreement (CDC RFA CE21-2104; CFDA 93.136) designed to reduce multiple forms of violence affecting adolescents and young adults, especially in communities experiencing high rates of violence. The central idea is to move beyond solely individual or relationship-focused interventions and instead prioritize prevention strategies at the outer layers of the social-ecological model, meaning community-level and societal-level changes. In practice, this pushes applicants to focus on broader conditions that shape violence risk and protection, such as neighborhood environments, local systems, policies, community norms, and cross-sector coordination.
The opportunity expects funded recipients to do several connected pieces of work rather than a single standalone program. Recipients must implement community/societal-level strategies that address multiple forms of violence impacting adolescents and young adults, not just one type in isolation. They also must develop and/or strengthen a jurisdiction-wide (or jurisdictional) violence prevention strategic plan, build and carry out a formal evaluation plan to measure implementation and outcomes, and create a sustainability plan that explains how the work will continue after federal funding ends. A required feature of PREVAYL is participation in a multi-sector coalition, reflecting the expectation that violence prevention at the community and societal levels requires coordinated action from partners such as public health, education, housing, local government, community-based organizations, youth-serving agencies, health care, and other stakeholders.
A defining emphasis of PREVAYL is addressing upstream risk factors tied to social determinants of health and racial inequity. The funding explicitly calls out conditions like concentrated poverty and limited educational or employment opportunities, recognizing that these structural factors can increase vulnerability to violence and limit access to protective resources. It also highlights racial inequity, including structural, systemic, and institutional racism, as a driver that must be acknowledged and confronted through prevention planning and community/societal strategies. In other words, applicants are expected to incorporate an equity lens and target root causes that shape community risk, rather than treating violence purely as an individual behavior problem.
Administratively, this is a discretionary federal grant administered by the U.S. Department of Health and Human Services through the Centers for Disease Control and Prevention, National Center for Injury Prevention and Control (CDC-NCIPC). The mechanism is a cooperative agreement, which typically indicates substantial CDC involvement through technical assistance, collaboration, and shared expectations around performance and reporting. The award ceiling listed is $250,000, with an anticipated eight awards. Eligibility is broad and includes state, county, and city governments; special districts; independent school districts; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities; nonprofits (with or without 501(c)(3) status); and for-profit entities, including small businesses, subject to any additional eligibility clarifications in the full announcement. The original posting date was March 2, 2021, and the original application deadline was May 1, 2021 (with electronic submissions due by 11:59 p.m. Eastern Time on the listed due date).Apply for CDC RFA CE21 2104
- The Department of Health and Human Services, Centers for Disease Control - NCIPC in the health sector is offering a public funding opportunity titled "Preventing Violence Affecting Young Lives (PREVAYL)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.136.
- This funding opportunity was created on Mar 02, 2021.
- Applicants must submit their applications by May 01, 2021 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $250,000.00 in funding.
- The number of recipients for this funding is limited to 8 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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PREVAYL Grant Opportunity FAQs
What is PREVAYL?
Preventing Violence Affecting Young Lives (PREVAYL) is a CDC-funded cooperative agreement (CDC RFA CE21-2104; CFDA 93.136) focused on reducing multiple forms of violence affecting adolescents and young adults, particularly in communities experiencing high rates of violence.
What is the main goal of this funding opportunity?
The main goal is to reduce violence affecting adolescents and young adults by prioritizing prevention strategies at the community and societal levels (the outer layers of the social-ecological model), rather than relying only on individual- or relationship-focused interventions.
What types of prevention approaches does PREVAYL prioritize?
PREVAYL prioritizes community-level and societal-level changes, such as improving neighborhood environments, strengthening local systems, influencing policies, shifting community norms, and building cross-sector coordination that can reduce violence risk and increase protective factors.
Does PREVAYL focus on one type of violence or multiple forms?
PREVAYL expects recipients to address multiple forms of violence impacting adolescents and young adults, not just one type in isolation.
What are the required components of the work under PREVAYL?
PREVAYL expects recipients to complete several connected pieces of work, including: implementing community/societal-level strategies addressing multiple forms of violence; developing and/or strengthening a jurisdiction-wide violence prevention strategic plan; building and implementing a formal evaluation plan to measure implementation and outcomes; and creating a sustainability plan describing how the work will continue after federal funding ends.
Is a violence prevention strategic plan required?
Yes. Recipients must develop and/or strengthen a jurisdiction-wide (or jurisdictional) violence prevention strategic plan as part of the funded work.
Is an evaluation plan required?
Yes. Recipients must build and carry out a formal evaluation plan to measure both implementation and outcomes.
Is a sustainability plan required?
Yes. Recipients must create a sustainability plan that explains how the work will continue after federal funding ends.
Is participation in a coalition required?
Yes. Participation in a multi-sector coalition is a required feature of PREVAYL.
What does "multi-sector coalition" mean in the context of PREVAYL?
It means coordinated work with partners from multiple sectors that influence community conditions tied to violence, such as public health, education, housing, local government, community-based organizations, youth-serving agencies, health care, and other stakeholders.
What is meant by focusing on the "outer layers" of the social-ecological model?
It means emphasizing prevention strategies that change broader community and societal conditions (like systems, policies, norms, and environments) that shape risk and protection, rather than only focusing on individual behavior change or relationship-level programming.
How does PREVAYL address equity and social determinants of health?
PREVAYL emphasizes addressing upstream risk factors connected to social determinants of health and racial inequity. The opportunity highlights structural conditions such as concentrated poverty and limited educational or employment opportunities, and it calls for acknowledging and confronting racial inequity, including structural, systemic, and institutional racism, through prevention planning and community/societal strategies.
What kinds of root causes are specifically called out in the opportunity description?
The description specifically calls out concentrated poverty, limited educational opportunities, limited employment opportunities, and racial inequity (including structural, systemic, and institutional racism) as factors that can increase vulnerability to violence and reduce access to protective resources.
Which federal agency administers PREVAYL?
PREVAYL is administered by the U.S. Department of Health and Human Services through the Centers for Disease Control and Prevention (CDC), National Center for Injury Prevention and Control (CDC-NCIPC).
What type of federal funding mechanism is PREVAYL?
PREVAYL uses a cooperative agreement mechanism, which typically indicates substantial CDC involvement through technical assistance, collaboration, and shared expectations for performance and reporting.
What is the award ceiling for PREVAYL?
The listed award ceiling is $250,000.
How many awards are anticipated?
The opportunity anticipates eight awards.
Who is eligible to apply?
Eligibility is broad and includes: state, county, and city governments; special districts; independent school districts; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities; nonprofits (with or without 501(c)(3) status); and for-profit entities, including small businesses, subject to any additional eligibility clarifications in the full announcement.
Can nonprofits apply if they do not have 501(c)(3) status?
Yes. The eligibility description explicitly includes nonprofits with or without 501(c)(3) status.
Can for-profit organizations apply?
Yes. For-profit entities, including small businesses, are listed as eligible, subject to any additional eligibility clarifications in the full announcement.
Are tribal governments and tribal organizations eligible?
Yes. Federally recognized tribal governments and other tribal organizations are included in the eligibility list.
Are schools and higher education institutions eligible?
Yes. Independent school districts, as well as public and private institutions of higher education, are included in the eligibility list.
Are public housing authorities eligible?
Yes. Public housing authorities are included in the eligibility list.
What is the CFDA number associated with this opportunity?
The CFDA number listed is 93.136.
What is the CDC funding announcement reference?
The CDC funding announcement reference is CDC RFA CE21-2104.
When was the opportunity originally posted?
The original posting date was March 2, 2021.
When was the original application deadline?
The original application deadline was May 1, 2021, with electronic submissions due by 11:59 p.m. Eastern Time on the listed due date.
What time zone applied to the electronic submission deadline?
The electronic submission deadline was listed as 11:59 p.m. Eastern Time on the due date.
What kinds of communities are especially emphasized for this work?
The opportunity especially emphasizes communities experiencing high rates of violence affecting adolescents and young adults.
Does PREVAYL allow a single standalone program approach?
No. The opportunity description indicates recipients are expected to carry out several connected pieces of work (strategies, strategic planning, evaluation, sustainability, and coalition participation) rather than implementing a single standalone program.
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