Opportunity Information: Apply for PAR 20 115
The Limited Competition: Centers of Biomedical Research Excellence (COBRE) Phase III - Transitional Centers (P30 Clinical Trial Optional) opportunity (Funding Opportunity Number PAR-20-115) is a National Institutes of Health (NIH) discretionary grant program designed to help established COBRE programs make the jump from NIH-supported center development into long-term independence. In practical terms, the FOA is focused on moving a COBRE beyond the earlier build-up phases by solidifying the center's shared research infrastructure (its cores) and the biomedical research activities that rely on those resources, so the overall program can remain productive and competitive even after COBRE-specific support ends. The central theme is sustainability: strengthening the operational footing, research capabilities, and institutional integration of the COBRE so that it can continue to serve investigators and attract ongoing funding through other mechanisms.
This FOA uses the P30 Center Core Grant structure, meaning the funding is aimed primarily at supporting shared core resources and the administrative framework that enables multiple research projects and investigators to function efficiently. Rather than operating like a typical single-project research grant, a P30 is built around the idea that shared facilities, services, technical expertise, and coordinated management can raise the quality and competitiveness of many research efforts at once. The "Phase III - Transitional Centers" framing signals that applicants are expected to already have a mature COBRE foundation and are now proposing a plan to transition that foundation into a stable, independently viable research center environment. The "Clinical Trial Optional" label indicates that clinical trials may be included if they fit the center's scope and meet NIH rules, but they are not required for the application.
Eligibility is limited and institution-focused. The listed eligible applicant type includes public and state-controlled institutions of higher education, and the announcement explicitly excludes foreign participation in several ways: non-U.S. (foreign) institutions cannot apply; non-domestic components of U.S. organizations are not eligible to apply; and foreign components, as defined in the NIH Grants Policy Statement, are not allowed under this FOA. These restrictions mean the proposed work, resources, and supported activities must be firmly based in the United States and within the eligible applicant organization, without a foreign component as part of the application structure.
From the opportunity data provided, the program is administered by NIH under CFDA number 93.859, within the broad funding activity category of health. The award ceiling is listed as $750,000, indicating the maximum budget level anticipated per award under this announcement. The source data lists the original closing date as 2022-05-27 and a creation date of 2020-02-20. The number of expected awards is not specified in the provided extract, which is common in some federal opportunity summaries when the agency does not commit to a fixed count or when it can vary by year and available appropriations.
Overall, the grant is best understood as a capstone-style COBRE mechanism intended to keep the center's most valuable and broadly used capabilities running beyond the developmental period, while positioning the institution and its investigators to compete successfully for other NIH and external support. The emphasis is less on starting new infrastructure from scratch and more on demonstrating that the existing COBRE-built platform is ready to operate as a stable, high-impact, institutionally embedded research center with a credible path to financial and scientific sustainability.Apply for PAR 20 115
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition: Centers of Biomedical Research Excellence (COBRE) Phase III - Transitional Centers (P30 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859.
- This funding opportunity was created on 2020-02-20.
- Applicants must submit their applications by 2022-05-27. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- Eligible applicants include: Public and State controlled institutions of higher education.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 20 115) also looked into and applied for these:
| Funding Opportunity |
|---|
| Maximizing Investigators Research Award (MIRA) for Early Stage Investigators (R35 - Clinical Trial Optional) Apply for PAR 20 117 Funding Number: PAR 20 117 Agency: National Institutes of Health Category: Health Funding Amount: $250,000 |
| Rational Design of Vaccines Against Hepatitis C Virus (U19 Clinical Trial Not Allowed) Apply for RFA AI 20 019 Funding Number: RFA AI 20 019 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Three-Dimensional (3D) Human Biomimetics for Infectious Diseases (U19 Clinical Trial Not Allowed) Apply for RFA AI 20 009 Funding Number: RFA AI 20 009 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Limited Competition: Research Centers in Minority Institutions (RCMI) Coordinating Center (U24 Clinical Trial Not Allowed) Apply for RFA MD 20 007 Funding Number: RFA MD 20 007 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Alzheimers Disease Sequencing Project Functional Genomics Consortium (U01 Clinical Trial Not Allowed) Apply for RFA AG 21 006 Funding Number: RFA AG 21 006 Agency: National Institutes of Health Category: Health Funding Amount: $1,000,000 |
| Multidisciplinary Studies to Improve Understanding of Influenza Transmission (U19 Clinical Trial Optional) Apply for RFA AI 20 008 Funding Number: RFA AI 20 008 Agency: National Institutes of Health Category: Health Funding Amount: $6,000,000 |
| Partnerships for the Development of Universal Influenza Vaccines (R21/R33 Clinical Trial Not Allowed) Apply for RFA AI 20 003 Funding Number: RFA AI 20 003 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Integrated Preclinical / Clinical AIDS Vaccine Development Program (IPCAVD) (U19 Clinical Trial Not Allowed) Apply for PAR 20 120 Funding Number: PAR 20 120 Agency: National Institutes of Health Category: Health Funding Amount: $3,000,000 |
| Exploring the Mechanisms Underlying Modulation of Glymphatic-Lymphatic Systems by Complementary and Integrative Health Approaches (R01 Clinical Trial Optional) Apply for RFA AT 21 001 Funding Number: RFA AT 21 001 Agency: National Institutes of Health Category: Health Funding Amount: $500,000 |
| Exploring the Mechanisms Underlying Modulation of Glymphatic-Lymphatic Systems by Complementary and Integrative Health Approaches (R21 Clinical Trial Optional) Apply for RFA AT 21 002 Funding Number: RFA AT 21 002 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Advancing HIV/AIDS Research within the Mission of the NIDCD (R21 Clinical Trial Optional) Apply for PAR 20 123 Funding Number: PAR 20 123 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIAMS Skin Biology and Diseases Resource-based Centers (P30 - Clinical Trial Not Allowed) Apply for RFA AR 21 003 Funding Number: RFA AR 21 003 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Harnessing Natural Killer (NK) Cells to Prevent, Control, or Eradicate HIV (R01 Clinical Trial Not Allowed) Apply for RFA AI 20 016 Funding Number: RFA AI 20 016 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Advancing HIV/AIDS Research within the Mission of the NIDCD (R01 Clinical Trial Optional) Apply for PAR 20 127 Funding Number: PAR 20 127 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Research Towards Developing a Cure for HBV in HIV/HBV Co-Infection (R21 Clinical Trial Not Allowed) Apply for PAS 20 121 Funding Number: PAS 20 121 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Advancing Vaccine Science to Improve Tuberculosis Treatment Outcomes for People Living With or Without HIV (R01 Clinical Trial Not Allowed) Apply for RFA AI 20 010 Funding Number: RFA AI 20 010 Agency: National Institutes of Health Category: Health Funding Amount: $800,000 |
| Engineering Immunity to HIV-1 Through Next Generation Vaccines (R61/R33 Clinical Trial Not Allowed) Apply for RFA AI 20 015 Funding Number: RFA AI 20 015 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIAMS Resource-based Centers for Bone, Muscle and Orthopaedic Research (BMOR) (P30 - Clinical Trials Not Allowed) Apply for RFA AR 21 004 Funding Number: RFA AR 21 004 Agency: National Institutes of Health Category: Health Funding Amount: $500,000 |
| Alzheimers Disease Research Centers (P30 Clinical Trial Not Allowed) Apply for RFA AG 21 019 Funding Number: RFA AG 21 019 Agency: National Institutes of Health Category: Health Funding Amount: $2,000,000 |
| Partnerships for Countermeasures against Select Pathogens (R01 Clinical Trials Not Allowed) Apply for RFA AI 20 028 Funding Number: RFA AI 20 028 Agency: National Institutes of Health Category: Health Funding Amount: $1,050,000 |
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