Opportunity Information: Apply for HRSA 25 063
The Health Resources and Services Administration (HRSA) funding opportunity HRSA-25-063, titled "Ending the HIV Epidemic in the U.S. - Ryan White HIV/AIDS Program (RWHAP) Parts A and B," is a discretionary cooperative agreement designed to concentrate HIV resources where the epidemic is most severe. The initiative targets 48 high-burden counties plus Washington, D.C. and San Juan, Puerto Rico, along with seven states identified as having a substantial rural HIV burden. The overall aim is to reduce new HIV infections in the United States by supporting effective, data-driven, and locally tailored strategies that improve HIV diagnosis, treatment outcomes, prevention, and outbreak response in the communities most impacted.
This opportunity sits under the broader federal "Ending the HIV Epidemic" (EHE) initiative, which is organized around four core strategies. First, it emphasizes diagnosing people with HIV as early as possible, because earlier diagnosis helps individuals start treatment sooner and reduces onward transmission. Second, it prioritizes rapid and effective treatment to achieve sustained viral suppression, which improves health outcomes and prevents sexual transmission when viral load is suppressed. Third, it supports prevention approaches that are already proven to work, strengthening the tools and services that stop new transmissions. Fourth, it focuses on responding quickly to potential HIV outbreaks so prevention and treatment resources can be deployed rapidly to the people and places that need them most.
HRSA leads the parts of EHE that connect testing, care, and treatment access through the Ryan White HIV/AIDS Program and the Health Center Program. In practical terms, HRSA-funded work under this announcement is expected to increase HIV testing and prevention among health center patients, strengthen pathways into HIV medical care, and ensure that people who are newly diagnosed or "re-identified" through testing programs are linked to treatment without delay. Another central responsibility described in the opportunity is outbreak response, meaning the capacity to identify emerging clusters and rapidly connect affected individuals to prevention and care services, rather than allowing transmission to accelerate.
Within the Ryan White HIV/AIDS Program specifically, the EHE investment is described as an expansion of the program's ability to meet client needs, with a very explicit focus on improving linkage to care and viral suppression. The funding is meant to help jurisdictions find and engage three key groups: people who are newly diagnosed with HIV, people who were diagnosed previously but are not currently in care, and people who are in care but have not yet achieved viral suppression. The expectation is that recipients will use the added resources to connect these individuals to the essential mix of HIV medical care, treatment, and support services that make it possible to stay in care and reach sustained viral suppression.
Eligibility is tightly tied to the geography and existing RWHAP award structure. For Part A, eligible applicants include RWHAP Part A-funded Eligible Metropolitan Areas (EMAs) or Transitional Grant Areas (TGAs) whose service areas include one or more of the identified 48 high-burden counties, as well as the EMAs of Washington, D.C. and San Juan, Puerto Rico. For Part B, eligibility includes the states and territories identified as having substantial rural HIV burden: Alabama, Arkansas, Kentucky, Mississippi, Missouri, Oklahoma, and South Carolina. The notice also specifies the RWHAP Part B program of the State of Ohio, applying on behalf of Hamilton County. In general, applicants must be domestic organizations, with "domestic" defined broadly to include the 50 states, D.C., Puerto Rico, U.S. territories, and several Pacific jurisdictions named in the announcement.
Operationally, this is a cooperative agreement rather than a standard grant, which typically signals a more active federal role in the project through substantial involvement, collaboration, or technical direction during implementation. The opportunity is listed under CFDA 93.686 and is categorized under the health funding activity area. The announcement anticipates 47 awards. The posting indicates an application closing date of October 22, 2024. The award ceiling is shown as 0 in the provided source data, which usually means a specific ceiling was not listed in that field rather than implying that funding is unavailable; applicants generally need to consult the full notice for budget parameters and expected award sizes.
Finally, the opportunity is explicitly framed as part of a multi-agency EHE effort. HRSA is described as working in coordination with the Centers for Disease Control and Prevention (CDC) and other federal partners including NIH Centers for AIDS Research (CFARs), the Indian Health Service (IHS), the Department of Housing and Urban Development (HUD), and the Substance Abuse and Mental Health Services Administration (SAMHSA). The intent is to align clinical care, public health surveillance and prevention, research capacity, housing supports, and behavioral health and substance use services so that high-burden jurisdictions can move faster toward fewer new infections, stronger linkage to care, and higher viral suppression rates.Apply for HRSA 25 063
- The Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Ending the HIV Epidemic in the U.S. – Ryan White HIV/AIDS Program Parts A and B" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.686.
- This funding opportunity was created on 2024-08-22.
- Applicants must submit their applications by 2024-10-22. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 47 candidate(s).
- Eligible applicants include: Others.
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FAQs: HRSA-25-063 - Ending the HIV Epidemic in the U.S. - RWHAP Parts A and B
What is HRSA-25-063?
HRSA-25-063 is a Health Resources and Services Administration (HRSA) discretionary cooperative agreement funding opportunity titled "Ending the HIV Epidemic in the U.S. - Ryan White HIV/AIDS Program (RWHAP) Parts A and B." It is designed to concentrate HIV resources in the U.S. communities where the epidemic is most severe, using data-driven and locally tailored strategies.
What is the main goal of this funding opportunity?
The overall aim is to reduce new HIV infections in the United States by supporting strategies that strengthen HIV diagnosis, improve treatment outcomes (including sustained viral suppression), expand effective prevention, and improve the ability to respond quickly to potential HIV outbreaks in the communities most impacted.
How does this opportunity relate to the federal Ending the HIV Epidemic (EHE) initiative?
This opportunity sits under the broader federal Ending the HIV Epidemic (EHE) initiative. It supports the EHE approach of focusing resources where HIV burden is highest and implementing strategies that improve diagnosis, treatment, prevention, and outbreak response.
What are the four core EHE strategies described in the opportunity?
The opportunity describes four EHE strategies: (1) diagnose people with HIV as early as possible, (2) treat HIV rapidly and effectively to achieve sustained viral suppression, (3) prevent new HIV transmissions using proven prevention approaches, and (4) respond quickly to potential HIV outbreaks so resources can be deployed rapidly where they are needed most.
What kinds of outcomes does the opportunity emphasize?
The opportunity emphasizes earlier diagnosis, rapid linkage to HIV medical care and treatment, improved retention and treatment outcomes, higher rates of sustained viral suppression, stronger prevention impact, and timely outbreak response capacity.
Which communities or jurisdictions are targeted by this opportunity?
The initiative targets 48 high-burden counties plus Washington, D.C. and San Juan, Puerto Rico, along with seven states identified as having a substantial rural HIV burden. The funding is intended to focus on the communities most impacted by HIV.
Which jurisdictions are eligible to apply under RWHAP Part A?
For Part A, eligible applicants include RWHAP Part A-funded Eligible Metropolitan Areas (EMAs) or Transitional Grant Areas (TGAs) whose service areas include one or more of the identified 48 high-burden counties, as well as the EMAs of Washington, D.C. and San Juan, Puerto Rico.
Which jurisdictions are eligible to apply under RWHAP Part B?
For Part B, eligible applicants include the states and territories identified as having a substantial rural HIV burden: Alabama, Arkansas, Kentucky, Mississippi, Missouri, Oklahoma, and South Carolina. The notice also specifies the RWHAP Part B program of the State of Ohio, applying on behalf of Hamilton County.
Is eligibility limited to domestic organizations?
Yes. Applicants must be domestic organizations. In the announcement, "domestic" is defined broadly to include the 50 states, Washington, D.C., Puerto Rico, U.S. territories, and several Pacific jurisdictions named in the opportunity.
What is a cooperative agreement, and why does it matter here?
This opportunity is a cooperative agreement rather than a standard grant. That typically means HRSA expects substantial federal involvement during implementation, such as active collaboration, technical direction, or ongoing engagement throughout the project period.
What program areas does HRSA lead within the EHE effort?
HRSA leads the EHE components that connect testing, care, and treatment access through the Ryan White HIV/AIDS Program and the Health Center Program. In practice, the announcement emphasizes improving testing and prevention among health center patients, strengthening pathways into HIV medical care, and ensuring prompt linkage to treatment for people who are newly diagnosed or re-identified through testing.
What does the opportunity say about HIV testing and linkage to care?
HRSA-funded work under this announcement is expected to increase HIV testing and prevention among health center patients, strengthen pathways into HIV medical care, and ensure that people who are newly diagnosed or re-identified through testing programs are linked to treatment without delay.
Who are the key populations the funding is meant to find and engage?
The funding is intended to help jurisdictions find and engage: (1) people who are newly diagnosed with HIV, (2) people diagnosed previously who are not currently in care, and (3) people who are in care but have not yet achieved viral suppression.
What is meant by "re-identified" through testing programs?
In the context provided, "re-identified" refers to people who already have an HIV diagnosis but are identified again through testing programs, with an emphasis on linking them to treatment without delay.
What is the funding expected to support within the Ryan White HIV/AIDS Program?
Within RWHAP, the EHE investment is described as an expansion of the program's ability to meet client needs, with an explicit focus on improving linkage to care and viral suppression. Recipients are expected to use added resources to connect priority groups to the essential mix of HIV medical care, treatment, and support services needed to stay in care and reach sustained viral suppression.
How does the opportunity define outbreak response?
Outbreak response is described as the capacity to identify emerging clusters and rapidly connect affected individuals to prevention and care services, rather than allowing transmission to accelerate.
How many awards does HRSA anticipate making?
The announcement anticipates 47 awards.
What is the application closing date?
The posting indicates an application closing date of October 22, 2024.
What is the CFDA number for this opportunity?
The opportunity is listed under CFDA 93.686.
What funding activity area is this opportunity categorized under?
The opportunity is categorized under the health funding activity area.
Is there an award ceiling (maximum funding amount) listed?
The award ceiling is shown as 0 in the provided source data. This typically indicates that a specific ceiling was not listed in that field, not that funding is unavailable. Applicants are expected to consult the full notice for budget parameters and expected award sizes.
Which federal partners are mentioned as part of the broader EHE coordination?
The opportunity states that HRSA is working in coordination with the Centers for Disease Control and Prevention (CDC) and other federal partners, including NIH Centers for AIDS Research (CFARs), the Indian Health Service (IHS), the Department of Housing and Urban Development (HUD), and the Substance Abuse and Mental Health Services Administration (SAMHSA).
Why does the opportunity emphasize multi-agency coordination?
The intent described is to align clinical care, public health surveillance and prevention, research capacity, housing supports, and behavioral health and substance use services so that high-burden jurisdictions can move faster toward fewer new infections, stronger linkage to care, and higher viral suppression rates.
What is the general approach recipients are expected to take?
Recipients are expected to implement effective, data-driven, and locally tailored strategies, focusing resources where HIV burden is highest and using the added capacity to strengthen diagnosis, linkage to care, treatment outcomes (including viral suppression), prevention, and outbreak response.
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