Opportunity Information: Apply for 75N99224R00001

Antigens Predicted for Broad Viral Efficacy through Computational Experimentation (APECx) is an ARPA-H funding opportunity focused on research and development aimed at identifying and advancing viral antigens with the potential to provide broad protection, using computational approaches as a central driver. The solicitation is issued by the Advanced Research Projects Agency for Health under Research and Development Solicitation No. 75N99224R00001, and it sits in the science and technology / R&D activity category (CFDA 93.384). The program framing signals an emphasis on ambitious, high-impact work that combines computational experimentation with downstream validation and development pathways, consistent with ARPA-Hs model of pushing toward actionable deliverables rather than purely exploratory studies.

The funding instrument listed for this opportunity is a cooperative agreement, which typically means substantial agency involvement is expected during performance, such as active program management, milestone tracking, and iterative technical direction. ARPA-H notes that it anticipates making multiple awards and that multiple award types may result from the announcement, suggesting the program may support a portfolio of performers working on different technical approaches, target virus families, modeling strategies, and validation pipelines.

The application process is structured in two stages and is not open proposal submission from the start. Applicants must first submit an abstract, and only those who submit an abstract can be considered for an invitation to submit a full proposal. Abstracts were due on December 15, 2023 at 9:00 AM Eastern Time. Full proposals are explicitly invite-only and were due on February 16, 2024 at 5:00 PM Eastern Time, which is also reflected as the original closing date in the source data. Eligibility is listed as unrestricted in the posting, but applicants are directed to the BAA/solicitation for the controlling eligibility and submission requirements.

ARPA-H encourages interested parties to review the attached APECx Research and Development Solicitation for full technical and administrative details, and to follow the opportunity posting for updates. Additional program context and public-facing information are available on the ARPA-H APECx program page at https://arpa-h.gov/engage/programs/apecx/. The posting also clarifies that the APEX Accelerators notice often shown on SAM.gov is a general small-business contracting resource message and is not related to the ARPA-H APECx program itself.

  • The Advanced Research Projects Agency for Health in the science and technology and other research and development sector is offering a public funding opportunity titled "Antigens Predicted for Broad Viral Efficacy through Computational Experimentation (APECx)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.384.
  • This funding opportunity was created on 2023-11-21.
  • Applicants must submit their applications by 2024-02-16. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Unrestricted.
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